- Current language: en
North West England
SATIN
Satiety Innovation
Liverpool
Health
The SATIN project has been devised to develop food products produced by novel food processing that control satiety through modification of food structure. To achieve this the SATIN project will:
1. Integrate advanced technologies to screen novel food structures through in vitro models to
isolate and refine products according to their satiating potential.
2. Develop novel food processing technologies that combine active ingredients and change food
structure to produce a range of novel satiety enhancing ingredients.
3. Produce finished foods products that pass through safety analysis, early sensory evaluation
and consumer testing.
4. Demonstrate the effects of prototype products on biomarkers of satiety and on nutrient
bioavailability using in vivo studies and validating new in vivo approaches.
5. Demonstrate the effects of final foods products on within-meal satiation, post-meal satiety and /
or reduced appetite and biomarkers of satiety.
6. Demonstrate the enduring effects of individual food products on satiety and their potential to
induce weight loss.
7. Demonstrate the long-term consumer and health benefits of adhering to a diet containing
satiety enhancing products.
8. Validate health claim endpoints and commercialise technologies and products.
The SATIN consortium consists of 7 SMEs and 4 commercial partners ensuring that advanced technologies developed to process and screen novel food products are applied to the food industry and improve European economic competitiveness. The safety and efficacy of products developed will be rigorously examined by 7 leading international academic research teams ensuring consumers will have new high quality processed foods to help them achieve a balanced diet.
http://cordis.europa.eu/project/rcn/101671_en.html
http://horizon-magazine.eu/article/extra-filling-foods-could-help-control-your-appetite_en.html
QWeCI
Quantifying Weather and Climate Impacts on Health in Developing Countries
Liverpool
Climate and environment
One of the most dramatic and immediate impacts of climate variation is that on disease, especially the vector-borne diseases that disproportionally affect the poorest people in Africa. Although we can clearly see that, for example, an El Nino event triggers Rift Valley Fever epidemics, we remain poor at understanding why particular areas are vulnerable and how this will change in coming decades, since climate change is likely to cause entirely new global disease distributions. This applies to most vector borne disease. At the same time, we do not know currently the limit of predictability of the specific climate drivers for vector-borne disease using state-of-the-art seasonal forecast models, and how best to use these to produce skilful infection-rate predictions on seasonal timescales. The QWeCI project thus aims to understand at a more fundamental level the climate drivers of the vector-borne diseases of malaria, Rift Valley Fever, and certain tick-borne diseases, which all have major human and livestock health and economic implications in Africa, in order to assist with their short-term management and make projections of their future likely impacts. QWeCI will develop and test the methods and technology required for an integrated decision support framework for health impacts of climate and weather. Uniquely, QWeCl will bring together the best in world integrated weather/climate forecasting systems with heath impacts modelling and climate change research groups in order to build an end-to-end seamless integration of climate and weather information for the quantification and prediction of climate and weather on health impacts in Africa.
http://cordis.europa.eu/project/rcn/93952_en.html
SysmedIBD
Systems medicine of chronic inflammatory bowel disease
Manchester
Health
Inflammatory bowel disease (IBD) is a major health problem with severe co-morbidities, requiring life-long treatment. Oscillating processes, like biological clocks are well studied and modeled in a number of systems. Circadian rhythms are extremely important for optimal treatments of patients. Recently, the NfkB pathway has been shown to be oscillating. In this project, we will model NfkB oscillation in chronic inflammatory bowel diseases in animal models and patient cohorts with immunosuppressive treatments and controls. The aim is to build an experimentally validated model the NfkB oscillation in 4D within the gut tissue. Dynamic, experimental validation will be done for various types of cells in the gut by a combination of methods, including single-cell based transcriptomics, multi-photon microscopy and time-dependent, multi-component profiling. The validated model framework will enable searching for critical components of the NfB oscillation and to assess their relevance for the disease in patients. Interfering with the oscillation of biological pathways may provide new possibilities to influence biological processes like inflammation. Hence, we will search (assisted by the models and databases developed) for small molecules interfering with the NfkB oscillation in chemical databases and validate selected candidates in experimental systems. To this end, we will use cell lines with the correct indicator constructs using high content microscopy. To better translate the findings in animal models to patients, we will use a mouse model with transplanted human tissue so that we can verify the mathematical model in human tissue and verify functionality of small molecules in vivo.
Owing to its systems, highly focused approach, the project will generate substantial insights into key mechanisms underlying IBD and will provide ways to modulate the oscillatory behavior of the NfB in IBD and IBD-dependent co-morbidities.
http://cordis.europa.eu/project/rcn/106178_en.html
Football Coaching as a Tool for Community Coaching
Manchester
Sport
This project used football due its power to help people to achieve more: address health issues, tackle racism, go back to school, find employment or become role models. Football can enhance individual development, self-confidence and conveys values of team spirit, fair play and responsibility. It teaches youth how to deal with victory and defeat, solve problems and accept rules.
DigiArt
A virtual museum
Liverpool
Research and innovation
DigiArt aims to create an "internet of historical things", available anywhere, at any time, on any web-enabled device. The project will provide a new, cost efficient solution to the capture, processing and display of cultural artefacts. It has been developed by a consortium of seven academic, industrial and museum partners and is being co-ordinated by researchers at Liverpool John Moores University.
The project's ambition is to present artefacts, linked to their context, in an immersive display with virtual and/or with augmented reality. This virtual reality will be the "story telling engine" that builds the context around the objects. The project, which received €1.84 million of its funding from the European Union under Horizon 2020, sets out to develop complex software to identify objects and automatically extract their meaning.
https://www.ljmu.ac.uk/about-us/news/a-virtual-museum
ARTIMATTER
Lego-Style Materials, Structures and Devices Assembled on Demand from Isolated Atomic Planes
Manchester
Research and innovation
At just one atom thick, Graphene is 200 times stronger than steel and has myriad applications, from helping to create bendable electronics and more efficient Solar cells to longer-life computers. The substance is the strongest, most impermeable and conductive material known to man. It was first discovered during ground-breaking experiments by Professors Kostya Novoselov and Andrew Geim a decade ago at the University of Manchester, for which both scientists were awarded the Nobel Prize for Physics in 2010. The European IMF has committed €1 billion to the Future and Emerging Technologies (FET) Graphene Flagship project, the largest-ever research initiative funded in the history of the EU.
Following the advent of graphene with its wide range of unique properties, several other one-atom-thick crystals have been isolated and their preliminary studies have been undertaken. This library of two-dimensional crystals opens a possibility to construct various 3D structures with on-demand properties, which do not exist in nature but can be assembled in Lego style by stacking individual atomic planes on top of each other in a desired sequence. This project is to explore this new avenue.
http://cordis.europa.eu/project/rcn/106411_en.html
http://www.graphene.manchester.ac.uk/collaborate/national-graphene-institute/
